Serena has been given to about 47,466 people in the United States since 1880. It was most common in 2000, which makes it a millennial-parent name.
Serena ranks 325th among American girls in 2025, with 942 born that year. Its best year was 2000, when 1,504 babies were given the name, ranking 209th. The typical living American called Serena is about 26 years old today. It is relatively most common in District of Columbia, where it accounts for 0.13% of births.
Source: US Social Security Administration, national and state name files, 2025 release, and the Office for National Statistics for England and Wales. Etymology researched and written by our editors. Living-population and median-age figures are our own estimates, described in the methodology.