Isyss has been given to about 599 people in the United States since 1880. It was most common in 2003, which makes it a millennial-parent name.
Its best year was 2003, when 133 babies were given the name, ranking 1468th. The typical living American called Isyss is about 20 years old today.
Source: US Social Security Administration, national and state name files, 2025 release. Etymology researched and written by our editors. Living-population and median-age figures are our own estimates, described in the methodology.